Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid

• Dong Cai,
• ZhiHua Zhang,
• Yufan Meng,
• KaiLi Zhu,
• LiYi Chen,
• ChangXiang Yu,
• ChangWei Yu,
• ZiYi Fu,
• DianShen Yang and
• YiXia Gong

Beilstein J. Org. Chem. 2020, 16, 798–808, doi:10.3762/bjoc.16.73

• -type pentacyclic triterpenoids, and the synthetic methods studied here can also apply to the modification of structurally similar other triterpenoic acids, but further experimental verification is needed. Results and Discussion The synthetic route to 18β-glycyrrhetinic acid piperazinyl amide 4 was

Genicunolide A, B and C: three new triterpenoids from Euphorbia geniculata

• Alia Farozi,
• Javid A. Banday and
• Shakeel A. Shah

Beilstein J. Org. Chem. 2015, 11, 2707–2712, doi:10.3762/bjoc.11.291

• . Keywords: Euphorbiaceae; Euphorbia geniculata; friedelin; friedelinol; genicunolide A; B; C; pentacyclic triterpenoids; Introduction Euphorbia (Euphorbiaceae) is a very large and diverse genus of flowering plants comprising of about 2,000 members and is found all over the world, ranging from short annual

Efficient oxidation of oleanolic acid derivatives using magnesium bis(monoperoxyphthalate) hexahydrate (MMPP): A convenient 2-step procedure towards 12-oxo-28-carboxylic acid derivatives

• Jorge A. R. Salvador,
• Vânia M. Moreira,
• Rui M. A. Pinto,
• Ana S. Leal and
• José A. Paixão

Beilstein J. Org. Chem. 2012, 8, 164–169, doi:10.3762/bjoc.8.17

• : bismuth(III) triflate; δ-hydroxy-γ-lactones; MMPP; oleanolic acid; triterpenoid; Findings The molecular diversity that arises from research into natural products represents a valuable tool for driving drug discovery and development [1][2]. In this context, pentacyclic triterpenoids are currently regarded

A simple route for renewable nano- sized arjunolic and asiatic acids and self- assembly of arjuna- bromolactone

• Braja G. Bag,
• Partha P. Dey,
• Shaishab K. Dinda,
• William S. Sheldrick and
• Iris M. Oppel

Beilstein J. Org. Chem. 2008, 4, No. 24, doi:10.3762/bjoc.4.24

• , triterpenoids have been recognized as renewables in supramolecular chemistry and nanoscience [5][6][7][8][9][10]. Even though the nano-sized triterpenic acids are available in abundance from a variety of plants, a major difficulty in their use is their availability in pure form. Occurrence of the pentacyclic

• triterpenoids having a β-amyrin skeleton with certain amounts of α-amyrins is common in nature and has been explained by 1,2-CH3 migration during their biosynthesis [11]. The mixture of the triterpenic acids extractable from Terminalia arjuna contains arjunolic acid as the major component along with asiatic